Fig. 4: Predicting methylation age in simulated and real single-cell data.
From: scEpiAge: an age predictor highlighting single-cell ageing heterogeneity in mouse blood
The predictions for epigenetic age shown in violin and boxplots in this figure have been made using the scEpiAge model for blood or liver described in Fig. 2, performances are shown in median absolute error (MAE). Boxplots show median levels and the first and third quartile, whiskers show 1.5× the interquartile range. A, B Predicted DNAme age of simulated blood (A) or liver (B) single cells. C, D Predicted DNAme age of pseudo-bulked real blood (C) and liver (D) single-cell data. E, F Predicted DNAme of the single-cell blood (E) and liver (F) data. The blood data is shown in red, and liver in green, the shading represents age (dark young, bright old). Created with BioRender.com released under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International license.
