Fig. 2: Structural and biological analysis of Omicron BA.2.86 subvariant.
From: Structural basis for the evolution and antibody evasion of SARS-CoV-2 BA.2.86 and JN.1 subvariants
a, b Surface presentation of domain-colored cryo-EM structures of extracellular domain of S protein (S-ECD) from Omicron BA.2.86, respectively, in complex with the PD of human ACE2, which show top and side view. Three RBDs are extended upward. ACE2 colored salmon. c Location of mutations detected in BA.2.86 spike, relative to its ancestral BA.2 (PDB: 7XO7). The red, cyan, orange, and laurel green mutations are in RBD, NTD, SD, and S2, respectively. The additional N-glycosylation sites colored in black. *deletion.
