Fig. 3: Interactions between SARS-CoV-2 BA.2.86-RBD and ACE2. | Nature Communications

Fig. 3: Interactions between SARS-CoV-2 BA.2.86-RBD and ACE2.

From: Structural basis for the evolution and antibody evasion of SARS-CoV-2 BA.2.86 and JN.1 subvariants

Fig. 3

a Cryo-EM density of the BA.2.86-RBD–ACE2 interface. The “up” RBD is shown in medium purple. The ACE2 is shown in salmon. This is an overall cryo-EM density of the RBD–ACE2 region. b The cryo-EM density map between the RBD and ACE2 interface. Residues are shown in sticks, with the corresponding cryo-EM density represented in mesh. c Overall structural model of Omicron RBD–ACE2-bound region. The regions enclosed by the red, green, and blue solid lines are illustrated in detail in (d). d Detailed analysis of the interface between RBD and ACE2. Polar interactions are indicated by yellow dotted lines.

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