Fig. 3: Individual model fits for cabamiquine–pyronaridine combination for the in vitro dug–drug–PD interaction assay data using IEV P. falciparum wild-type field isolates. | Nature Communications

Fig. 3: Individual model fits for cabamiquine–pyronaridine combination for the in vitro dug–drug–PD interaction assay data using IEV P. falciparum wild-type field isolates.

From: Towards clinically relevant dose ratios for Cabamiquine and Pyronaridine combination using P. falciparum field isolate data

Fig. 3

Model predictions from the final model (lines) and original data (points) for each parasite (colors); each facet displays a studied scenario for cabamiquine (A1) and pyronaridine (A2). The numbers in each facet present the concentration of either cabamiquine or pyronaridine in nM in each well. Readout: total SYBR Green and MitoTracker positive parasite count.

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