Fig. 5: Characterizing PaD-like dioxygenases (PaDLs) as a family of hydroquinone dioxygenases. | Nature Communications

Fig. 5: Characterizing PaD-like dioxygenases (PaDLs) as a family of hydroquinone dioxygenases.

From: Substrate specificity of a branch of aromatic dioxygenases determined by three distinct motifs

Fig. 5

a Promiscuity profile substrate scope of PaD, MtaD, PaDL1, and PaDL2. PaDL1 and PaDL2 were selected from the same cluster of PaD. The active proteins are marked below the tested hydroquinones. b The BGC and proposed biosynthetic pathway of multicolosic acid. c Sequence similarity network (SSN) analysis of PaDLs. The SSN uses 2730 PaDLs obtained from uniport database by searching for Duf4243-domain containing proteins.

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