Fig. 3: Temporal evolutionary trends in VpST3 collection.

a Bayesian Skyline Plot showing estimated effective population size for LatAm-VpST3, with upper and lower bounds of the 95% highest posterior density interval. b Prevalence of each sub-group in Latin America over time shows patterns of shifting dominance. While LatAm-VpST3 remained dominant in Latin America compare to the Asian-dominant group, in recent years LatAm-VpST3 is being replaced with the modern group. c Decline in average mutations per core genome in LatAm-VpST3 over time (averaged across isolates found in the same year). d Trend in total gene count over time for isolates within each of the three clusters.