Fig. 3: A subpopulation of muscle progenitors exhibits a dual somite-derived myogenic cell/LPM cell signature in emu forelimb buds. | Nature Communications

Fig. 3: A subpopulation of muscle progenitors exhibits a dual somite-derived myogenic cell/LPM cell signature in emu forelimb buds.

From: Immobilization secondary to cell death of muscle precursors with a dual transcriptional signature contributes to the emu wing skeletal pattern

Fig. 3

a, d, tSNE plots of body trunk at the forelimb level of stage 20/21 emu embryo data (a) and stage 25 emu forelimb buds (d), respectively. b, e, Dot plots of subcluster marker gene expression of stage 20/21 data (b) and stage 25 data (e), respectively. Dot color represents the average expression level, and dot size represents the percentage of cells expressing marker genes. c, f, Venn diagram showing number of cells expressing Pax3 and/or Hand2 in the muscle cluster of stage 20/21 data (c) and stage 25 data (f), respectively. g, Violin plots showing the expression levels of Pax3, Lbx1, MyoD1, Tnnt3, Hand2, Prrx1, and Tbx5 in Pax3 + /Hand2- cells, and Pax3 + /Hand2+ cells in the muscle cluster of stage 25 emu forelimb data. The two-sided Wilcoxon rank sum-test was used for statistical test. The exact p-values are indicated.

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