Fig. 4: Causalities in the two-sample two-direction Mendelian randomization analyses between the CPS/CPA and psychiatric disorders. | Nature Communications

Fig. 4: Causalities in the two-sample two-direction Mendelian randomization analyses between the CPS/CPA and psychiatric disorders.

From: Cognitive processing speed and accuracy are intrinsically different in genetic architecture and brain phenotypes

Fig. 4

The forest plot showed significant causalities in the solid square with different estimation methods. Effective sample size was 92983 and 57604 for MDD and Schizophrenia, respectively. CPS cognitive processing speed, CPA cognitive processing accuracy. The error band indicates ± 95% CI of the causal effect in the Mendelian randomization analyses. Significant results were defined as Bonferroni corrected p < 0.05. See Supplementary Data 12 for the exact p-values.

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