Fig. 3: An overview of the metabolic pathways associated to the core genes underlying the BD-1.2 and BD-2 lineages separation.

All genes annotated were found to have reduced flux span through the metabolic system when knocked out. Genes coloured in blue have a significant different allelic distribution between BD-1.2 and BD-2, associated metabolic pathways are labelled in purple. All 3D protein structures were generated in Alphafold123 under a Creative Commons Attribution 4.0 license (CC-BY 4.0), no changes were made.