Table 1 Differentially methylated and expressed genes associated with ontogeny

From: DNA Methylation signatures underpinning blood neutrophil to lymphocyte ratio during first week of human life

Symbol

RegionType

Gene

Correlation

P-Value

adjPValue

RHOH

promoters

ENSG00000168421

− 0.76

2.31E-228

1.41E-226

DENND2D

promoters

ENSG00000162777

− 0.75

1.01E-221

2.05E-220

ART4

promoters

ENSG00000111339

− 0.75

7.80E-217

1.19E-215

CD3D

promoters

ENSG00000160654

− 0.70

2.81E-176

2.14E-175

LCK

promoters

ENSG00000182866

− 0.69

1.17E-170

6.47E-170

DGKA

promoters

ENSG00000065357

− 0.68

9.51E-167

4.83E-166

CHI3L2

promoters

ENSG00000064886

− 0.68

7.88E-164

3.43E-163

CD28

promoters

ENSG00000178562

− 0.67

2.87E-161

1.10E-160

PCED1B

promoters

ENSG00000179715

− 0.67

1.22E-159

4.38E-159

IL32

promoters

ENSG00000008517

− 0.65

3.37E-148

1.03E-147

BACH2

promoters

ENSG00000112182

− 0.65

5.14E-148

1.49E-147

TTC39C

promoters

ENSG00000168234

− 0.64

7.26E-141

1.93E-140

FYN

promoters

ENSG00000010810

− 0.63

7.19E-135

1.76E-134

CLEC2D

promoters

ENSG00000069493

− 0.60

8.38E-121

1.83E-120

S100A8

promoters

ENSG00000143546

− 0.60

4.02E-118

8.17E-118

BASP1

promoters

ENSG00000176788

− 0.59

1.69E-116

3.22E-116

RCAN3

promoters

ENSG00000117602

− 0.59

1.98E-115

3.67E-115

HAL

promoters

ENSG00000084110

− 0.59

1.49E-114

2.53E-114

RUNX3

promoters

ENSG00000020633

− 0.58

1.06E-109

1.66E-109

CDC25B

promoters

ENSG00000101224

− 0.57

2.02E-104

2.93E-104

NFE2

promoters

ENSG00000123405

− 0.55

6.87E-97

9.53E-97

SCML4

promoters

ENSG00000146285

− 0.55

1.02E-96

1.39E-96

FAM69A

promoters

ENSG00000154511

− 0.55

2.92E-96

3.88E-96

FAM134B

promoters

ENSG00000154153

− 0.54

1.30E-91

1.58E-91

TP53I11

promoters

ENSG00000175274

− 0.52

1.43E-85

1.61E-85

FAR2

promoters

ENSG00000064763

− 0.52

1.59E-83

1.71E-83

CD226

promoters

ENSG00000150637

− 0.51

2.77E-82

2.86E-82

CD82

promoters

ENSG00000085117

− 0.51

7.45E-80

7.57E-80

  1. Correlation: Pearson’s correlation coefficient between lead CpG in DMR (most significant) and transcript expression for genes within 1.5 kb from the DMR. P-values are shown from the Pearson’s coefficient test. P-values adjusted by False Discovery Rate.
  2. An Abbreviated list of gene promoter associations is shown here, a complete set of regions in Supplementary Data 1.
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