Table 2 Top 10 enriched Reactome pathways in the ontogeny protein-protein interaction network

Immune System

2.11E-60

2.88E-57

Adaptive Immune System

4.25E-53

2.90E-50

Antigen processing: Ubiquitination & Proteasome degradation

6.17E-29

2.80E-26

Class I MHC-mediated antigen processing & presentation

2.25E-27

7.68E-25

Signaling by the B Cell Receptor (BCR)

4.66E-27

1.27E-24

Signaling by ERBB4

2.30E-25

5.21E-23

Signaling by Interleukins

1.74E-24

3.40E-22

Cytokine Signaling in the Immune System

1.65E-23

2.81E-21

Innate Immune System

1.39E-22

2.11E-20

Signaling by SCF-KIT

2.20E-22

2.99E-20

Downstream Signaling Events Of B Cell Receptor (BCR)

2.53E-22

3.14E-20

Signaling by EGFR in Cancer

4.85E-21

5.51E-19

Signaling by NGF

5.58E-20

5.85E-18

Signaling by EGFR

6.40E-20

6.23E-18

Downstream signal transduction

4.34E-18

3.95E-16

Signaling by ERBB2

6.10E-18

4.89E-16

DAP12 signaling

6.10E-18

4.89E-16

TCR signaling

1.14E-17

8.63E-16

DAP12 interactions

1.91E-17

1.37E-15

Interleukin-3, 5 and GM-CSF signaling

9.04E-17

6.16E-15