Fig. 2: Alternative histones are diverse and found across prokaryotes. | Nature Communications

Fig. 2: Alternative histones are diverse and found across prokaryotes.

From: Histones and histone variant families in prokaryotes

Fig. 2

a Clustered sequence space of prokaryotic histones. Clustering was performed with CLANS. The color of each line indicates the sequence similarity between the two sequences; sequences that are connected by darker lines are more similar than those connected by lighter lines. Clusters are colored based on the histone category to which they belong as determined by the AlphaFold2 predictions. For a short description of each histone category, see Supplementary Table 2. b Cladogram of archaea showing the distribution of nucleosomal (Nuc), face-to-face (FtF), coiled-coil (CC), and Methanococcales (Mc) histones across different phyla. The cladogram is based on GTDB version 207. For reference, Methanobacteriota A contains the Methanopyri and Methanococci classes; Methanobacteriota B contains the Thermococci and the Methanofastidiosa classes.

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