Fig. 4: ZZ-type zinc finger histones can possibly bind two zinc ions. | Nature Communications

Fig. 4: ZZ-type zinc finger histones can possibly bind two zinc ions.

From: Histones and histone variant families in prokaryotes

Fig. 4

a The ZZ-histone D0LYE7 from Haliangium ochraceum SMP-2 as predicted by AlphaFold2. ZZ-histones contain a ZZ-type zinc finger domain at the N-terminus and an α3 histone fold at the C-terminus. Each residue is colored by its pLDDT value. b The ZZ domain of D0LYE7. This domain contains two zinc binding motifs, one C4 motif (C20, C23, C51, C53) and a C2H2 motif (C36, C41, H59, H65). These residues correspond to C10, C13, C41, and C43 for the C4 motif and C26, C31, H49, and H55 for the C2H2 motif in the HMM profile (Supplementary Fig. 18). Each residue is colored by its pLDDT value. c The ZZ domain of HERC2 (gray, PDB: 6WW435) aligned to D0LYE7.

Back to article page