Fig. 7: IHF histones are functionally related to IHF. | Nature Communications

Fig. 7: IHF histones are functionally related to IHF.

From: Histones and histone variant families in prokaryotes

Fig. 7

a The homodimer of IHF histone A0A358AGI2 from Candidatus Omnitrophica as predicted by AlphaFold2. Each residue is colored by its pLDDT value. b Gene cluster comparison of bacterial metagenomes that contain the IHF histone. The organism and its genome ID are noted on the left. The IHF histone, IHF-like, and topoisomerase VI-like genes are colored green, orange, and blue respectively. c The monomer of IHF-like A0A358AGI6 from Candidatus Omnitrophica as predicted by AlphaFold2. Each residue is colored by its pLDDT value. Residue R45 is highlighted in green. d The RxTxxxxD motif and the “sprocket” R32 of IHF histone A0A358AGI2. R32, R65, T67, and D72 relate to R24, R57, T59, and D64 in the IHF histone HMM logo (Supplementary Fig. 34).

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