Fig. 1: Overview concept and material design of the bioabsorbable electrical stimulation suture (BioES-suture) for treating muscle gashes.
From: A bioabsorbable mechanoelectric fiber as electrical stimulation suture
a The desired tissue recovery process when treating the gashes, including suturing the wound, electrical stimulation to accelerate healing, and in vivo absorption of suture. The BioES-suture generated electric field through the muscle deformation at the wound for electrical stimulation. Accelerated wound healing by promoting tissue regeneration, ECM deposition and vascularization under the synergistic effect of mechanical suturing and electrical stimulation. b A photo of the BioES-suture. Scale bar: 2 cm. c The mciroscale morphology of the (i) pre-assembled core fiber, (ii) PLGA nanofibers and (iii) BioES-suture. Scale bar: 250 µm in optical photographs and 2 µm in scanning electron microscope (SEM) image. d Comparison of normalized cell viability for 7 days showing excellent biocompatibility of the BioES-suture. n = 3 independent samples for each group, data represent mean ± standard deviation.
