Fig. 2: Determination of reaction rates for L- and D- products for 15 ribozymes.
From: Prebiotic chiral transfer from self-aminoacylating ribozymes may favor either handedness
For each ribozyme, the fraction of RNA aminoacylated by L- (red) and D- (blue) BFO was measured at multiple concentrations of BFO and fit to the pseudo-first-order rate law as described, to estimate the enantioselectivity index ie = log2(kD/kL). Each point represents one experimental replicate. Replicates are jittered horizontally for visibility. Lines show the best fits to the rate law. Shaded areas indicate 95% confidence intervals from bootstrapping analysis. Source data are provided as a Source Data file. BFO = biotinyl-Phe-5(4H)-oxazolone.
