Fig. 4: Sequence relationships and stereoselectivity of ribozymes.
From: Prebiotic chiral transfer from self-aminoacylating ribozymes may favor either handedness
A The enantioselectivity index is shown as a heat map, with each ribozyme represented by a labeled circle. The Levenshtein edit distance (number of substitutions, insertions, or deletions) between sequences is indicated by the line strength (see legend). Direction of preference is conserved among related ribozymes. B Pairwise differences in enantioselectivity vs. edit distance for each pair of ribozymes. Blue: between ribozymes within Motif 1; red: between ribozymes within Motif 2; purple: between ribozymes of Motifs 1 and 2; green: between ribozymes of Motifs 1 and 3; orange: between ribozymes of Motifs 2 and 3. C Stereoselectivity of D- vs. L-ribozyme S-1A.1-a. Bars indicate the mean of triplicates; error bars indicate the standard error of the mean. The enantiomeric excesses [ee = |(FD − FL)/(FD + FL)|], were not significantly different (two-sided t-test, p = 0.11). Source data are provided as a Source Data file. F = fraction; ie = enantioselectivity index.
