Fig. 8: Validation of overall explain CT change in ABCD and IMAGEN datasets.
From: Regional patterns of human cortex development correlate with underlying neurobiology
Explained spatial CT change variance in ABCD and IMAGEN data. The overall model performance is illustrated as scatter plots contrasting predicted CT change (y axis) with observed CT change (x axis). Scatters: single brain regions, color-coded by prediction error. Continuous line: linear regression fit through the observations. Dashed line: theoretical optimal fit. Brains: prediction errors corresponding to scatters. Rows: upper: cohort-average predicted by the reference (Braincharts) model, lower sample size due to subjects dropped during model adaptation (see Methods); middle: observed cohort-average (ComBat-harmonized); lower: observed single-subject values (ComBat-harmonized), one regression model was calculated for each subject, but the results were combined for illustration purposes. CT cortical thickness, adj. adjusted. Group-level source data are provided as a Source Data file.
