Fig. 7: In vivo transcriptomics analysis. | Nature Communications

Fig. 7: In vivo transcriptomics analysis.

From: Biodegradable oxygen-evolving metalloantibiotics for spatiotemporal sono-metalloimmunotherapy against orthopaedic biofilm infections

Fig. 7

a GO term analysis of upregulated terms after treatment with MnPM + US on day 3. Pink, highlight. b KEGG enrichment of upregulated genes after treatment with MnPM + US on day 3. GSEA of representative immune signaling pathways about NF-kappa B (c), NOD-like receptor (d), cytosolic DNA-sensing (e), IL17 (f), TNF (g) after treatment with MnPM + US on day 3. h GO term analysis of upregulated terms after treatment with MnPM + US on day 10. Pink, highlight. i, KEGG enrichment of upregulated genes after treatment with MnPM + US on day 10. GSEA of representative repair signaling pathways about DNA replication (j), cell cycle (k), ribosome biogenesis in eukaryotes (l), mismatch repair (m), nucleotide excision repair (n) after treatment with MnPM + US on day 10. Source data are provided as a Source Data file.

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