Fig. 1: Selected applications of disulfides and poly(disulfide)s.
From: SO2F2 mediated click chemistry enables modular disulfide formation in diverse reaction media
A Disulfide-containing nature product, Kottamide E, and drug, Romidepsin. B Thiol-mediated uptake of cell-penetrating poly(disulfide)s. C Disulfide bonds as cleavable linkers in antibody-drug conjugates. D Disulfide cross linked hydrogel.
