Fig. 1: Circadian rhythm of delta power is diminished in brain areas with pathology.
From: Diminished circadian and ultradian rhythms of human brain activity in pathological tissue in vivo
a–c From subject A: (a) The circadian rhythm of delta power, obtained by applying a band-pass filter to isolate the power of the signal with a period between 19 and 31 hours. Pathological tissue is shown in red. Bars indicate the relative power of the signal in each ROI. b The relative power in each brain area, pathological tissue is outlined in red. c The relative power of the circadian rhythm in pathological tissue compared to other tissue. An AUC of 0.92 is calculated when using this relative power to predict pathology. d The AUC of each subject for the same prediction. An AUC > 0.5 indicates that the rhythm is diminished in pathological tissue. Dashed lines indicate median and quartiles of the distribution. Brain plots from ref. 50. Source data are provided as a Source Data file.
