Table 1 Summary of identified promoter regions and their overlap with open chromatin regions and histone marks indicating promoter regions and active transcription in CanFam4

From: The DoGA consortium expression atlas of promoters and genes in 100 canine tissues

promoter set

all promoters

primary

alternative

novel

robust

46,644

15,654

16,596

14,394

comprehensive

106,681

24,4978

40,282

41,421

epigenetic marks

all robust promoters

primary

alternative

novel

ATAC-seq

55.2%

75.0%

47.9%

42.3%

H3K27ac

54.9%

71.7%

53.1%

12.9%

H3K4me3

35.3%

59.2%

29.5%

5.4%

  1. The robust promoter set is a subset of all the identified promoters with very high reproducibility across replicates. The highest-expressed promoter region of a gene was classified as primary; additional promoters, if present, were categorized as alternative promoters. The percentage of robust promoter regions overlapping with open chromatin and histone marks is with the respective subset of samples (see methods for specification of tissues).