Table 1 Multiple-deletion strains
From: Minimisation of metabolic networks defines a new functional class of genes
Class of genes | Double mutant | Triple mutant | Quadruple mutant |
|---|---|---|---|
Magnificent Seven combinations | ynk1Δ/gpt2Δ | ynk1Δ/gpt2Δ/tps2Δ | |
gpt2Δ/tps1Δ | ynk1Δ/gpt2Δ/tps1Δ | ||
gpt2Δ/cho1Δ | gpt2Δ/tps1Δ/tps2Δ | ||
ynk1Δ/cho1Δ | gpt2Δ/cho1Δ/tps1Δ | ||
Magnificent Seven triple mutant (ynk1Δ/gpt2Δ/tps2Δ) + Δ ARO genes combinations | ynk1Δ/gpt2Δ/tps2Δ/aro1Δ | ||
ynk1Δ/gpt2Δ/tps2Δ/aro2Δ | |||
ynk1Δ/gpt2Δ/tps2Δ/aro7Δ | |||
Non-NED combinations | chs1Δ/dnf3Δ | chs1Δ/dnf3Δ/htd2Δ | chs1Δ/dnf3Δ/htd2Δ/coq5Δ |
chs1Δ/htd2Δ | chs1Δ/dnf3Δ/suc2Δ | chs1Δ/dnf3Δ/htd2Δ/zta1Δ | |
dnf3Δ/suc2Δ | suc2Δ/chs1Δ/htd2Δ | chs1Δ/dnf3Δ/suc2Δ/coq5Δ | |
dnf3Δ/htd2Δ | chs1Δ/dnf3Δ/suc2Δ/zta1Δ | ||
suc2Δ/chs1Δ | |||
suc2Δ/htd2Δ | |||
Non-NED triple mutant (chs1Δ/dnf3Δ/suc2Δ) + aro7Δ combination | chs1Δ/dnf3Δ/suc2Δ/aro7Δ |
