Fig. 4: Profound glycerophosholipid remodeling in orthoflavivirus infection.
From: Glycerophospholipid remodeling is critical for orthoflavivirus infection
a Analysis of the lipidomics dataset using BioPan pathway analysis. Lipid species abundance (Supplementary Data 1, sheet pmol_ug) was used for the analysis. Predicted reaction activities between lipid classes are indicated by arrows (red indicates increased and blue decreased reaction activities). Color of lipid classes indicate log2 fold change in abundance per µg protein of infected versus uninfected cells (n = 3 independent experiments). b Upper left triangle: BioPan prediction of Z scores of active (red) and suppressed (blue) enzyme activities using the standard settings (Z > 1.645 at p < 0.05)28,93. Lower right triangle: log2 fold change of expression level determined by transcriptome analysis of the same samples. Source data are provided as a Source Data file.
