Table 1 The response analysis and survival time of all patients
 | All patients (n = 48) | Second-line (n = 31) | ≥third-line (n = 17) | ||
---|---|---|---|---|---|
Best overall response, n (%) | |||||
CR | 2 (4.2) | 2 (6.5) | 0 (0) | ||
PR | 12 (25.0) | 8 (25.8) | 4 (23.5) | ||
SD | 17 (35.4) | 9 (29.0) | 8 (47.1) | ||
PD | 17 (35.4) | 12 (38.7) | 5 (29.4) | ||
ORR, % (95% CI) | 29.2 (17.0–44.1) | 32.3 (16.7–51.4) | 23.5 (6.8–49.9) | ||
DCR, % (95% CI) | 64.6 (49.5–77.8) | 61.3 (42.2–78.2) | 70.6 (44–89.7) | ||
mPFS (95%CI), months | 4.0 (2.6–5.4) | 4.0 (2.4–5.6) | 3.8 (1.2–6.4) | ||
mOS (95%CI), months | 11.1 (5.7–16.5) | 14.5 (8.4–20.6) | 7.6 (5.4–9.8) |