Fig. 8: Transcriptional analysis of anti-tumor mechanism induced by Pd2Sn@GOx-SP.
From: Intermetallics triggering pyroptosis and disulfidptosis in cancer cells promote anti-tumor immunity
a Cluster diagram of DEGs between Pd2Sn@GOx-SP + laser and control groups. b Volcano plots and c numbers of the upregulated and downregulated genes of Pd2Sn@GOx-SP + laser groups compared with control groups. Statistical significance is assessed by two-sided t-test. d KEGG pathway enrichment analysis. e The circle diagram of GO enrichment analysis. Statistical significance is assessed by one-sided t-test. f GSEA of pyroptosis signaling pathway. Statistical significance is assessed by one-sided t-test. g Cluster heatmap of the DEGs associated with disulfidptosis between Pd2Sn@GOx-SP + laser and control groups. Source data are provided as a Source Data file (n = 3 mice).
