Fig. 4: DNA binding thermodynamics of OC2 base-specific mutants.
From: The homeodomain regulates stable DNA binding of prostate cancer target ONECUT2
a–c ITC binding analysis of OC2SQ, OC2N and OC2RR, to PEG10 DNA. The raw heats (differential power, DP) for each injection are shown on top and binding isotherms are shown in the bottom. The data shown is representative of three independent experiments (n = 3; technical replicates). Source data are provided as a Source Data file.
