Table 2 Heat capacity analysis of OC2 and CUT binding to the PEG10 DNA
From: The homeodomain regulates stable DNA binding of prostate cancer target ONECUT2
Interaction | Temp (°C) | ΔG (kcal/mol) | ΔH (kcal/mol) | -TΔS (kcal/mol) | ΔC° (cal/mol/K) |
|---|---|---|---|---|---|
|  | 12 | −9.8 ± 0.5 | −12.5 ± 0.2 | 2.7 ± 0.5 |  |
OC2 - PEG10 | 25 | −11.2 ± 0.2 | −15.5 ± 0.3 | 4.4 ± 0.2 | −440.7 ± 46.3 |
|  | 30 | −10.9 ± 0.5 | −20.4 ± 1.0 | 9.5 ± 1.0 |  |
|  | 12 | −7.5 ± 0.2 | −2.1 ± 0.2 | −5.4 ± 0.3 |  |
CUT - PEG10 | 25 | −7.8 ± 0.1 | −3.4 ± 0.2 | −4.4 ± 0.3 | −74.1 ± 6.8 |
|  | 30 | −7.9 ± 0.1 | −3.4 ± 0.3 | −4.4 ± 0.4 |  |
