Table 4 Kinetics analysis of wild-type and mutant OC2 proteins to the PEG10 DNA

From: The homeodomain regulates stable DNA binding of prostate cancer target ONECUT2

Interaction

ka (M−1s−1)

kd (s−1)

OC2 - PEG10

320000 ± 123000

0.0005 ± 0.0001

OC2SQ - PEG10

256000 ± 60100

0.0036 ± 0.0014

OC2N - PEG10

360000 ± 36700

0.0030 ± 0.0007

OC2RR - PEG10

162000 ± 101000

0.0028 ± 0.0010