Table 1 Baseline characteristics of subjects in the training and validation cohorts
From: Identifying septic shock subgroups to tailor fluid strategies through multi-omics integration
Variables | Total, (n = 494) | Training cohort, (n = 352) | Validation cohort, (n = 142) | p |
|---|---|---|---|---|
Age, median (Q1, Q3) | 71 (60, 81) | 71 (59, 81) | 72 (64, 82) | 0.173 |
Sex, male (%) | 313 (63) | 224 (64) | 89 (63) | 0.922 |
Height (cm), Median (Q1, Q3) | 165 (158, 171) | 165 (158, 172) | 165 (158, 170) | 0.275 |
Weight (kg), Median (Q1, Q3) | 60 (55, 70) | 60 (55, 70) | 60 (54, 69.25) | 0.502 |
Infection site, n (%) | <0.001 | |||
Abdomen | 75 (15) | 39 (11) | 36 (25) | |
Biliary/liver | 54 (11) | 31 (9) | 23 (16) | |
Brain | 4 (1) | 3 (1) | 1 (1) | |
Intestine | 26 (5) | 16 (5) | 10 (7) | |
Lung/chest | 186 (38) | 146 (41) | 40 (28) | |
Others | 51 (10) | 44 (12) | 7 (5) | |
Soft tissue | 20 (4) | 18 (5) | 2 (1) | |
Urinary | 78 (16) | 55 (16) | 23 (16) | |
SOFA, median (Q1, Q3) | 9 (7, 12) | 9 (7, 12) | 9.5 (7, 12) | 0.179 |
CRP (mg/dl), median (Q1, Q3) | 140.52 (64.5, 217.03) | 138.75 (63.97, 211.08) | 147.31 (72.62, 238.12) | 0.406 |
Lactate (mmol/L), median (Q1, Q3) | 3 (1.9, 5) | 2.67 (1.7, 4.52) | 3.55 (2.42, 6.2) | <0.001 |
Fluid intake (ml/day), median (Q1, Q3) | 3045 (1980, 4455.3) | 2950 (1917, 4310) | 3306.5 (2044.25, 4956.75) | 0.081 |
Urine (ml/day), median (Q1, Q3) | 1000 (377.5, 1862.5) | 1027.5 (427.5, 1950) | 850 (303.75, 1667.5) | 0.063 |
Mortality, n (%) | 79 (16) | 64 (18) | 15 (11) | 0.051 |
Hospital days, median (Q1, Q3) | 13.27 (9, 23.53) | 13.54 (9, 24) | 13 (8.05, 22) | 0.404 |
