Table 1 New-onset autoantibodies with >1% prevalence

From: Prevalent and persistent new-onset autoantibodies in mild to severe COVID-19

Gene

Protein

Antigen

ENSP

aa

New-onset

Acute onset (%)

Baseline seronegative (%)

n

%

CCDC63

Coiled-coil domain-containing protein 63

HPRR3070734

ENSP00000312399

155–249

49

10

96

78

SNURF

SNRPN upstream reading frame protein

HPRR4280292

ENSP00000463201

45–69

49

10

76

49

TRIM63

E3 ubiquitin-protein ligase TRIM63

HPRR3760711

ENSP00000363390

182–246

44

9

66

80

CALU

Calumenin

HPRR4180820

ENSP00000249364

74–128

32

6

41

59

TPO

Thyroid peroxidase

HPRR4180385

ENSP00000329869

867–932

22

4

95

59

PCYT1B

Choline-phosphate cytidylyltransferase B

HPRR4320357

ENSP00000368439

329–369

22

4

86

77

MYO16

Unconventional myosin-XVI

HPRR3090005

ENSP00000401633

843–923

18

4

89

33

AQP4

Aquaporin-4

HPRR2140210

ENSP00000372654

253–323

17

3

35

41

NPC1

NPC intracellular cholesterol transporter 1

HPRR620021

ENSP00000269228

448–580

14

3

79

50

NBEAL2

Neurobeachin-like protein 2

HPRR3460329

ENSP00000415034

1865–1939

13

3

100

38

ZNF688

Zinc finger protein 688

HPRR3610292

ENSP00000223459

95–166

12

2

92

42

IFNA6

Interferon alpha-6

HPRR3360040

ENSP00000369558

74–99

12

2

25

42

SIGLECL1

SIGLEC family-like protein 1

HPRR3420383

ENSP00000469601

11–94

10

2

90

60

MTG2

Mitochondrial ribosome-associated GTPase 2

HPRR3300084

ENSP00000359859

317–390

10

2

80

70

NEDD8

NEDD8

HPRR2760190

ENSP00000250495

7–67

10

2

70

50

KIF15

Kinesin-like protein KIF15

HPRR2960531

ENSP00000324020

671–748

10

2

60

70

FABP3

Fatty acid-binding protein, heart

HPRR3890315

ENSP00000362817

30–58

9

2

67

56

ANO2

Anoctamin-2

HPRR3070036

ENSP00000507275

79–167

9

2

56

56

LARP1

La-related protein 1

HPRR3760556

ENSP00000428589

254–329

9

2

44

56

ORC2

Origin recognition complex subunit 2

HPRR2920267

ENSP00000234296

150–224

8

2

75

62

C6orf141

Uncharacterized protein C6orf141

HPRR2660035

ENSP00000434602

5–73

7

1

86

86

PTPRZ1

Receptor-type tyrosine-protein phosphatase zeta

HPRR4170025

ENSP00000377047

441–534

6

1

50

100

  1. New-onset autoantibodies were assessed in 502 individuals (456 HCW and 46 hospitalized COVID-19 patients, after exclusion of outlying or incomplete data).