Table 1 New-onset autoantibodies with >1% prevalence
From: Prevalent and persistent new-onset autoantibodies in mild to severe COVID-19
Gene | Protein | Antigen | ENSP | aa | New-onset | Acute onset (%) | Baseline seronegative (%) | |
---|---|---|---|---|---|---|---|---|
n | % | |||||||
CCDC63 | Coiled-coil domain-containing protein 63 | HPRR3070734 | ENSP00000312399 | 155–249 | 49 | 10 | 96 | 78 |
SNURF | SNRPN upstream reading frame protein | HPRR4280292 | ENSP00000463201 | 45–69 | 49 | 10 | 76 | 49 |
TRIM63 | E3 ubiquitin-protein ligase TRIM63 | HPRR3760711 | ENSP00000363390 | 182–246 | 44 | 9 | 66 | 80 |
CALU | Calumenin | HPRR4180820 | ENSP00000249364 | 74–128 | 32 | 6 | 41 | 59 |
TPO | Thyroid peroxidase | HPRR4180385 | ENSP00000329869 | 867–932 | 22 | 4 | 95 | 59 |
PCYT1B | Choline-phosphate cytidylyltransferase B | HPRR4320357 | ENSP00000368439 | 329–369 | 22 | 4 | 86 | 77 |
MYO16 | Unconventional myosin-XVI | HPRR3090005 | ENSP00000401633 | 843–923 | 18 | 4 | 89 | 33 |
AQP4 | Aquaporin-4 | HPRR2140210 | ENSP00000372654 | 253–323 | 17 | 3 | 35 | 41 |
NPC1 | NPC intracellular cholesterol transporter 1 | HPRR620021 | ENSP00000269228 | 448–580 | 14 | 3 | 79 | 50 |
NBEAL2 | Neurobeachin-like protein 2 | HPRR3460329 | ENSP00000415034 | 1865–1939 | 13 | 3 | 100 | 38 |
ZNF688 | Zinc finger protein 688 | HPRR3610292 | ENSP00000223459 | 95–166 | 12 | 2 | 92 | 42 |
IFNA6 | Interferon alpha-6 | HPRR3360040 | ENSP00000369558 | 74–99 | 12 | 2 | 25 | 42 |
SIGLECL1 | SIGLEC family-like protein 1 | HPRR3420383 | ENSP00000469601 | 11–94 | 10 | 2 | 90 | 60 |
MTG2 | Mitochondrial ribosome-associated GTPase 2 | HPRR3300084 | ENSP00000359859 | 317–390 | 10 | 2 | 80 | 70 |
NEDD8 | NEDD8 | HPRR2760190 | ENSP00000250495 | 7–67 | 10 | 2 | 70 | 50 |
KIF15 | Kinesin-like protein KIF15 | HPRR2960531 | ENSP00000324020 | 671–748 | 10 | 2 | 60 | 70 |
FABP3 | Fatty acid-binding protein, heart | HPRR3890315 | ENSP00000362817 | 30–58 | 9 | 2 | 67 | 56 |
ANO2 | Anoctamin-2 | HPRR3070036 | ENSP00000507275 | 79–167 | 9 | 2 | 56 | 56 |
LARP1 | La-related protein 1 | HPRR3760556 | ENSP00000428589 | 254–329 | 9 | 2 | 44 | 56 |
ORC2 | Origin recognition complex subunit 2 | HPRR2920267 | ENSP00000234296 | 150–224 | 8 | 2 | 75 | 62 |
C6orf141 | Uncharacterized protein C6orf141 | HPRR2660035 | ENSP00000434602 | 5–73 | 7 | 1 | 86 | 86 |
PTPRZ1 | Receptor-type tyrosine-protein phosphatase zeta | HPRR4170025 | ENSP00000377047 | 441–534 | 6 | 1 | 50 | 100 |