Table 1 Demographics of the final fMRI sample

From: Cognitive reserve against Alzheimer’s pathology is linked to brain activity during memory formation

 

N

Age (years)

Sex (% female)

Education (years)

PACC5

PL

CN

152

68.89 (5.1)

63.2

14.57 (2.7)

0.21 (0.5)

0.33 (0.2)

ADR

51

66 (4.7)

56.9

14.49 (2.8)

0.14 (0.7)

0.3 (0.2)

SCD

202

70.01 (5.9)

44.6

15.2 (2.9)

−0.04 (0.7)

0.4 (0.3)

aMCI

64

72.62 (4.8)

53.1

13.44 (2.8)

−1.22 (0.8)

0.58 (0.3)

ADD

21

73.36 (5.4)

66.7

13.71 (2.8)

−2.97 (1.2)

0.84 (0.2)

All

490

69.73 (5.6)

53.7

14.64 (2.9)

−0.19 (1.0)a

0.42 (0.3)b

  1. Values represent the mean (standard deviation).
  2. Source data are provided as a Source Data file.
  3. ADD mild Alzheimer’s disease dementia, ADR AD patient first-degree relatives, aMCI amnestic mild cognitive impairment, CN cognitively normal, SCD subjective cognitive decline, PACC5 Preclinical Alzheimer’s Cognitive Composite 5, PL pathological load.
  4. aNine participants did not have PACC5 scores.
  5. b258 participants did not have PL scores due to missing CSF data.
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