Fig. 5: Mutational profile of 73 copy number alteration (CNA)-quiet and 71 CNA-other oral cavity SCC (OCSCC).
From: Hallmarks of a genomically distinct subclass of head and neck cancer
a Oncoplot of somatic variants of 15 most prevalent genes in 144 OCSCC samples with 73 CNA-quiet on the left (fraction genome altered (FGA) < 0.20 and < 6 called segments) and 71 CNA-other OCSCC (FGA ≥ 0.20 and/or ≥ 6 called segments) on the right. Colors represent somatic variant classifications, see Supplementary Data 8. b Two-sided fisher’s exact test to compare mutations between CNA-quiet and -other OCSCC. Raw as well as adjusted p-value (using Benjamini-Hochberg false discovery rate) are displayed; ten genes with lowest p-value are displayed and ordered based on their p-value. Details can be found in Supplementary Data 4. Also, source data are provided with this paper.
