Fig. 7: The in vivo antifungal ability of PCW on a C. albicans-induced wound infection model in mice. | Nature Communications

Fig. 7: The in vivo antifungal ability of PCW on a C. albicans-induced wound infection model in mice.

From: Synergistic wall digestion and cuproptosis against fungal infections using lywallzyme-induced self-assembly of metal-phenolic nanoflowers

Fig. 7

a The scheme illustrated the construction of the murine skin fungal infection model and the treatment protocol with different formulations. b Photos of mice wounds after different treatments on the 1st, 2nd, 3rd, 5th, and 7th day. c C. albicans colony counting of wound tissue after different treatments on the 3rd day (n = 3 independent experiments). d Visual graph of wound area changes after different treatments. e Statistical results of wound areas after different treatments (n = 6 independent experiments). f SEM images of wound tissues after different treatments on the 7th day. g H&E staining and IL-6 staining images of wound tissues after different treatments. HE a common histological staining technique; IL-6 inflammatory cytokines. f, g showed one of three independent experiments with similar results. Data for (c, e) were presented as mean values ± SD. error bars = SD. Significance of (c, e) were calculated by one-way ANOVA with Tukey’s post hoc test. Source data were provided in Source Data file.

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