Table 1 Status Epileptics Parameters
Phase | Parameters | KA-Veh | KA-PPA | p-Value |
---|---|---|---|---|
Phase 1 | Lag Time before First Seizure | 0.9 ± 0.3 h | 3.9 ± 0.8 h | 0.004 |
Duration of Phase 1 | 4.8 ± 1.5 h | 10.0 ± 1.6 h | 0.038 | |
Total Number of Seizures | 10.1 ± 2.0 | 14.0 ± 1.4 | 0.142 | |
Duration of Seizures | 115.0 ± 20.6 s | 204.2 ± 17.3 s | <0.001 | |
Interval between Seizures | 8.2 ± 1.4 min | 20.3 ± 2.5 min | 0.001 | |
Racine Scale (maximum hourly score) | 5.5 ± 0.1 |  5.1 ± 0.1 | 0.029 | |
Phase 2 | Onset of Phase 2 | 5.7 ± 1.4 h | 14.6 ± 1.4 h | 0.001 |
Duration of Phase 2 | 22.5 ± 3.2 h | 8.6 ± 2.6 h | 0.007 | |
Peak of Spike Frequency | 0.8 ± 0.1 Hz | 0.7 ± 0.1 Hz | 0.201 | |
Time of Peak Frequency from KA infusion | 9.0 ± 1.2 h | 18.1 ± 2.2 h | 0.003 | |
Racine Scale (maximum hourly score) | 2.1 ± 0.6 | 1.3 ± 0.2 | 0.380 | |
Duration of Phase 1 + Phase 2 | 26.1 ± 4.2 h | 19.9 ± 2.0 h | 0.265 |