Table 1 Status Epileptics Parameters

From: Enhancing glymphatic fluid transport by pan-adrenergic inhibition suppresses epileptogenesis in male mice

Phase

Parameters

KA-Veh

KA-PPA

p-Value

Phase 1

Lag Time before First Seizure

0.9 ± 0.3 h

3.9 ± 0.8 h

0.004

Duration of Phase 1

4.8 ± 1.5 h

10.0 ± 1.6 h

0.038

Total Number of Seizures

10.1 ± 2.0

14.0 ± 1.4

0.142

Duration of Seizures

115.0 ± 20.6 s

204.2 ± 17.3 s

<0.001

Interval between Seizures

8.2 ± 1.4 min

20.3 ± 2.5 min

0.001

Racine Scale (maximum hourly score)

5.5 ± 0.1

 5.1 ± 0.1

0.029

Phase 2

Onset of Phase 2

5.7 ± 1.4 h

14.6 ± 1.4 h

0.001

Duration of Phase 2

22.5 ± 3.2 h

8.6 ± 2.6 h

0.007

Peak of Spike Frequency

0.8 ± 0.1 Hz

0.7 ± 0.1 Hz

0.201

Time of Peak Frequency from KA infusion

9.0 ± 1.2 h

18.1 ± 2.2 h

0.003

Racine Scale (maximum hourly score)

2.1 ± 0.6

1.3 ± 0.2

0.380

Duration of Phase 1 + Phase 2

26.1 ± 4.2 h

19.9 ± 2.0 h

0.265

  1. P-values were calculated by unpaired two-tailed t-test.