Fig. 3: Characterization of the sprayable and in-situ formed fibrin gel. | Nature Communications

Fig. 3: Characterization of the sprayable and in-situ formed fibrin gel.

From: A wearable and stretchable dual-wavelength LED device for home care of chronic infected wounds

Fig. 3

a Pictures show sprayable and film-formed performance of F-gel. b, Representative scanning electron micrographs of F-gel c, d, Rheological properties of F-gel. e Release profile of TQ and NADH from F-gel (n = 3 biologically independent samples). f Absorption spectra of TQ, NADH and spectrum of rLED and bLED. g, h Excitation and emission spectra of TQ, NADH (g) and F-gel (h). i, j, H2O2 (i) and ·OH (j) were generated by F-gel in combination with bLED (n = 5 biologically independent samples in each group). k ·OH, O2·- or 1O2 adducts identified and measured by EPR. l Transmittance of F-gel (n = 3 biologically independent samples in each group). m, n Adhesive properties of F-gel. o, Schematic illustration of the protective effect of NADH on cells during PDT. p, Cell viability of HUVECs after different treatments (n = 5 biologically independent samples in each group). q, r Statistical analysis (q) and representive graphs (r) of intracellular ROS (n = 5 biologically independent samples in each group). Data are presented as mean values ± SEM. Statistical significance and P values were determined by two-way ANOVA followed by Dunnett’s multiple comparison test (i,j) or one-way ANOVA followed by Tukey’s multiple comparison test (p,q). Parts of panel a and panel o was created with BioRender.com released under a Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International license.

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