Fig. 3: Proposed biosynthesis pathway of alligamycin A (1) and B (2).
From: Alligamycin A, an antifungal β-lactone spiroketal macrolide from Streptomyces iranensis
Proposed biosynthesis pathway of alligamycin A (1) and B (2). Figure shows the type one module PKS with five core genes responsible for alligamycin biosynthesis. Abbreviation: KS, ketosynthase; AT, acyltransferase; DH, dehydratase; ER, enoylreductase; KR, ketoreductase; ACP, acyl carrier protein; TE, thioesterase.
