Fig. 2: Activation of the androgen receptor leads to a delayed increase in histone modifications and chromatin accessibility.
From: Decoding the epigenetics and chromatin loop dynamics of androgen receptor-mediated transcription
A Trimmed mean of M values (TMM) normalized ChIP-seq or ATAC-seq or Start-seq signal were compared across all time points at different regulatory elements, including: Promoters of AR upregulated genes (P + AR: red), promoters of AR-independent genes (P-AR: black), AR-bound enhancers (E + AR: yellow) of AR-regulated genes, AR-free enhancers (E-AR: gray) of AR-independent genes. B A similar analysis was done for the promoters of AR-downregulated genes (P+dAR: blue), and their AR-bound enhancers (E+dAR: yellow). For all figures, the solid line represents the mean, and the error bars indicate the 95% confidence.
