Fig. 7: RNA sequencing analysis of hMSCs in high ROS-level microenvironment. | Nature Communications

Fig. 7: RNA sequencing analysis of hMSCs in high ROS-level microenvironment.

From: Electron-donable heterojunctions with synergetic Ru-Cu pair sites for biocatalytic microenvironment modulations in inflammatory mandible defects

Fig. 7

a PCA analysis between samples. b Hierarchical clustering of differentially expressed genes from the hMSCs after different treatments. c Enriched KEGG pathways of H2O2 versus Ru-Cu/EDHJ + H2O2. d Enriched GO terms of H2O2 versus Ru-Cu/EDHJ + H2O2. e (e1–e9) GSEA analysis of H2O2 versus Ru-Cu/EDHJ + H2O2. In (c, d), p-value obtained from one-sided Hypergeometric test without multiple comparisons. In (e), p-value obtained from one-sided Permutation test without multiple comparisons. In (e), NES indicates the normalized enrichment score. Experiments were repeated independently three times with similar results. Source data are provided as a Source Data file.

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