Fig. 2: Salt bridges are abundant across all 28 human collagens.

A Schematic depiction of the sequence constraint for salt bridge formation between the leading (orange), middle (green) and trailing (blue) chains of a triple helix [pdb: 6q3p45]. B The total number of salt bridges (blue) and interruptions (yellow) observed in the triple-helical domain of each collagen subtype. C A visual representation of the distribution of salt bridges (blue), KGE or KGD triplets (light blue), and interruptions (yellow) in the triple-helical domains of human collagens.