Fig. 7: Mechanistic investigation of the accelerated porcine diabetic wound healing.

a CLSM images of wound regions in different treatments stained with DHE (images are representative of 6 biologically independent samples). Scale bar: 200 μm. b The relative mRNA expression levels of inflammatory-related genes in the wound homogenates of porcine (n = 6 biologically independent samples). c Masson staining of wound tissues receiving different treatments on Day 18 (images are representative of 6 biologically independent samples). Scale bar: 1 mm. d The relative mRNA expression levels of proliferative, angiogenesis, and collagen production-related genes in the wound homogenates of porcine (n = 6 biologically independent samples). All data were presented as the mean ± SEM. Statistical significance was determined using a one-way ANOVA test followed by Tukey’s multiple comparison analysis.