Fig. 2: Cryo-EM structures of hUT-A2, hUT-A3, hUT-B and zf-UT. | Nature Communications

Fig. 2: Cryo-EM structures of hUT-A2, hUT-A3, hUT-B and zf-UT.

From: Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters

Fig. 2

a–d Overall cryo-EM densities and structures of hUT-A2 (a), hUT-A3 (b), hUT-B (c) and zf-UT (d) homotrimer. The cryo-EM densities of different UTs are displayed on the phospholipid bilayer cell membrane with the represent cartoon models shown below. Molecules bound to the extracellular and intracellular sides of different UTs, along with their corresponding EM densities, are indicated in dashed circles at the top and bottom layers, respectively. Created in BioRender. Huang, S. (2024) https://BioRender.com/h99o001.

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