Table 1 Participant characteristics for UKB data on eGFR-trajectories

From: Analyzing longitudinal trait trajectories using GWAS identifies genetic variants for kidney function decline

 

UKB 150K

UKB 350K

% (n) of women

53.7 (80,091)

53.7 (187,129)

Number of eGFR assessments per person

6 (2–289)

1 (1–289)

Follow-up time [years]

8.4 (1.0–27.1)

0.0 (0.0–27.1)

Age at 1st assessment [years]

55.9 (35.0–76.4)

57.1 (35.0–78.2)

Age at last assessment [years]

65.1 (37.0–79.7)

60.9 (36.0–79.7)

eGFR at 1st assessment [mL/min/1.73 m2]

98.0 (15.2–192.1)

97.4 (15.0–192.1)

eGFR at last assessment [mL/min/1.73 m2]

89.4 (15.0–198.6)

94.0 (15.0–198.6)

% (n) with CKD at 1st assessment

0.7 (1038)

1.2 (4069)

% (n) with CKD at any assessment

3.8 (13,116)

4.6 (16,147)

  1. We show descriptive statistics for UKB individuals with ≥2 eGFR assessments (UKB 150K; n = 149,263, m = 1,321,370) and for the extended data adding individuals with =1 eGFR assessment (UKB 350K: n = 348,275; m = 1,520,382). The 199,012 individuals with =1 eGFR assessment have median age 58.2 (min–max 36.0–78.2) years and median eGFR 97.0 (min–max 15.0–159.6) mL/min/1.73 m2. CKD was defined as eGFR < 60 mL/min/1.73 m2. Shown is % (n) or median (min–max).
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