Table 2 ECG characteristics from A/A mice treated with continuous epinephrine injection and overexpression APOE
OE-APOE | E | E + OE-APOE | |||||||
|---|---|---|---|---|---|---|---|---|---|
Time (Days) | 0 | 1 | 3 | 0 | 1 | 3 | 0 | 1 | 3 |
HR (bpm) | 452 ± 28 | 400 ± 13 | 485 ± 36 | 432 ± 28 | 539 ± 33 | 481 ± 75 | 474 ± 24 | 496 ± 22 | 491 ± 31 |
PR (msec) | 40.4 ± 3.9 | 46.3 ± 4.8 | 43.8 ± 3.5 | 42.3 ± 2.1 | 44.4 ± 3.2 | 48.5 ± 11 | 46.2 ± 2.7 | 48.6 ± 4.41 | 49 ± 5.2 |
QT (msec) | 29.6 ± 3.1 | 29.9 ± 2.9 | 30.4 ± 1.39 | 29.9 ± 1.2 | 28.2 ± 2.9 | 36.7 ± 6.2 | 31.3 ± 2.6 | 31.3 ± 2.6 | 33.8 ± 1.6 |
QTc | 28.3 ± 1.9 | 24.4 ± 2.7 | 27.2 ± 1.25 | 25.3 ± 1.0 | 26.7 ± 3.2 | 32.3 ± 2.7 | 28.6 ± 1.2 | 28.5 ± 3.0 | 30.5 ± 2.1 |
QRS (msec) | 15.2 ± 2.1 | 13.0 ± 0.6 | 12.4 ± 1.6 | 12.8 ± 1.07 | 12.1 ± 0.19 | 12.5 ± 1.30 | 12.8 ± 1.46 | 12.5 ± 0.62 | 12.5 ± 0.75 |
AmpP (mv) | 0.11 ± 0.01 | 0.08 ± 0.01 | 0.08 ± 0.01 | 0.09 ± 0.01 | 0.07 ± 0.01 | 0.06 ± 0.01 | 0.08 ± 0.02 | 0.09 ± 0.01 | 0.09 ± 0.03 |
AmpQ (mv) | −0 ± 0.01 | −0 ± 0.01 | −0 ± 0.01 | −0 ± 0.01 | −0 ± 0.01 | −0 ± 0.01 | −0 ± 0.01 | −0 ± 0.01 | −0 ± 0.01 |
AmpR (mv) | 0.92 ± 0.06 | 0.86 ± 0.16 | 0.89 ± 0.16 | 0.95 ± 0.15 | 0.80 ± 0.11 | 0.88 ± 0.13 | 0.94 ± 0.16 | 0.78 ± 0.13 | 0.78 ± 0.09 |
AmpS (mv) | −0.18 ± 0.05 | −0.08 ± 0.01 | −007 ± 0.01 | −0.06 ± 0.08 | −0.07 ± 0.02 | −0.06 ± 0.02 | −0.06 ± 0.02 | −0.04 ± 0.01 | −0.05 ± 0.01 |