Fig. 6: Bioactivities and pharmacokinetic parameter of crizotinib glucosides.
From: Stereoselective chemical N-glycoconjugation of amines via CO2 incorporation
Pharmacokinetic parameters were tested after oral application of crizotinib (50 mg/kg) and GA95 (91.6 mg/kg) to healthy male C57 mice, results are the mean ± SD of 3 subjects in each group. a Analyte: crizotinib; b analyte: GA95. Me, methyl; Ac, acetyl.
