Fig. 7: Trapping of blockers in the closed pore of GluK2 receptor.
From: Trapping of spermine, Kukoamine A, and polyamine toxin blockers in GluK2 kainate receptor channels
Frontal section of the TMD surface in the GluK2PhTx74 (a), GluK2NpTx8 (b), GluK2KukoA (c), GluK2SPM (d) and GluK2Open (e, PDB ID: 9B35) structures, with the blocker molecules shown as space-filling models (green) and residues contributing to the selectivity filter and gate shown in sticks (yellow). The surface is colored by electrostatic potential, blue being positively charged, red negatively charged, and white neutral.
