Table 1 M. abscessus susceptibilities (MIC, µg/ml) to antimicrobials
Strain | GD276 | GD276-2 | GD276-1 | GD276p1 | GD276p2 | GD276p3 | GD276p4 |
Morphotype | Mixeda | Smooth | Rough | Smooth | Rough | Smooth | Smooth |
Source | Chest swab | Sternum | Sternum | Chest swab | Chest swab | Chest swab | Skin Biopsy |
Amikacin | 16 (S)b | 16 (S) | 16 (S) | 16 (S) | 16 (S) | 16 (S) | 32 (I) |
Bedaquiline | 0.06 | ND | ND | 0.12 | 0.12 | 0.12 | 0.12 |
Cefoxitin | 64 (I) | 32 (I) | 128 (R) | 128 (R) | 32 (I) | 32 (I) | 32 (I) |
Ciprofloxacin | >16 (R) | >4 (R) | 4 (R) | >4 (R) | >4 (R) | >4 (R) | >4 (R) |
Clarithromycin | 16 (R) | 16 (R) | >16 (R) | >16 (R) | >16 (R) | >16 (R) | >16 (R) |
Clofazimine | 0.25 | 0.25 | 0.25 | 0.25 | 0.12 | 0.25 | 0.5 |
Doxycycline | >8 (R) | >8 (R) | >8 (R) | >8 (R) | >8 (R) | >8 (R) | >8 (R) |
Eravacycline | ND | ND | ND | 0.12 | ND | 0.12 | 0.12 |
Imipenem | 16 (I) | 8 (I) | 16 (I) | 16 (I) | 8 (I) | 16 (I) | 16 (I) |
Linezolid | 16 (I) | 16 (I) | 16 (I) | 4 (S) | 16 (I) | 16 (I) | 16 (I) |
Moxifloxacin | >4 (R) | >4 (R) | >4 (R) | >4 (R) | >4 (R) | >4 (R) | >4 (R) |
Omadacycline | ND | ND | ND | 0.5 | 0.5 | 0.12 | 0.12 |
Tedizolid | ND | ND | ND | ND | ND | 4 | <0.6 |
Tigecycline | 0.25 | 0.12 | 0.25 | 0.25 | 0.25 | 0.25 | 0.25 |
TMP-SMX | >4 (R) | 4 (R) | >4 (R) | 4 (R) | >4 (R) | >4 (R) | >4 (R) |
