Fig. 5: Neutrophils supersede tumorigenic signaling to drive reinvigoration of antitumor immunity.
From: Copper chelation redirects neutrophil function to enhance anti-GD2 antibody therapy in neuroblastoma
a Overrepresentation analysis of pathways relatively enriched in TEPA-treated immune cell clusters compared to control, presented as nodes with associated genes as branches using single-cell RNA sequencing. b Circle plot of the aggregated cell-cell communication networks in control and TEPA-treated single-cell samples. Edge width is proportional to the number of ligand-receptor interactions between cell types. c Scatter plots comparing the outgoing and incoming interaction strengths between control and TEPA-treated samples.
