Fig. 6: MEC center-distance cells encode relative distance.
From: Allocentric and egocentric spatial representations coexist in rodent medial entorhinal cortex
a Representative responses of egocentric and allocentric cells in recording environments of different sizes. (i) A representative center-bearing cell recorded across consecutive sessions in small (S, 1 m × 1 m), large (L, 1.5 m × 1.5 m), and small (S’, 1 m × 1 m) enclosures. (ii) Same as (i) but for a center-distance cell. (iii) Same as (i) but for a head-direction cell. Directional tuning curves have MVL values inset, and distance tuning curves have R2 of the center distance - firing rate relationship inset. b Distribution of angular shift in preferred firing directions for 34 head-direction cells between the first small enclosure session and large enclosure session. c The same as b but for 20 center-bearing cells. d Comparison of distance tuning slopes between the first small enclosure session and large enclosure session for 16 center-distance cells. e Ratio of distance tuning slopes between the first small enclosure session and large enclosure session for 16 center-distance cells. Two-sided Wilcoxon signed-rank test, S-L, Z = -3.41, P < 0.01; L-S’, Z = -3.19, P < 0.01; S-S’, Z = -1.93, P = 0.05. Data are presented as mean values +/- SEM. f–h Comparison of peak firing rates across recording sessions for 34 head-direction cells (f ), 20 center-bearing cells (g) and 16 center-distance cells (h). Two-sided Wilcoxon signed-rank test, head-direction cells, S-L, Z = -1.24, P = 0.22; L-S’, Z = -0.65, P = 0.52; S-S’, Z = -1.07, P = 0.29; center-bearing cells, S-L, Z = -1.61, P = 0.11; L-S’, Z = -1.16, P = 0.25; S-S’, Z = -0.22, P = 0.82; center-distance cells, S-L, Z = -1.24, P = 0.22; L-S’, Z = -1.86, P = 0.06; S-S’, Z = -0.78, P = 0.44. The box plot represents the interquartile range (IQR), with the lower and upper edges indicating the first (Q1) and third quartiles (Q3), respectively. The line inside the box marks the median (Q2). The whiskers extend to the smallest and largest values within 1 times the IQR from Q1 and Q3. Source data are provided as a Source Data file.
