Fig. 6: Applied performance of the PEG-IL-based microreactor in the kinetic resolution of various racemic alcohols. | Nature Communications

Fig. 6: Applied performance of the PEG-IL-based microreactor in the kinetic resolution of various racemic alcohols.

From: Engineering enzyme conformation within liquid-solid hybrid microreactors for enhanced continuous-flow biocatalysis

Fig. 6

a Schematic illustration of the continuous-flow biocatalysis. b 1-(3,5-Bis(trifluoromethyl)phenyl)ethanol as a substrate. c TGA curve and SEM image of the hybrid catalyst after reaction. d–i Different racemic alcohols as substrates: d 2-octanol, e 6,10-dimethylundeca-5,9-dien-2-ol, f 1-(4-methyl phenyl)ethanol, g 4-phenyl-2-butanol, h 1-indanol, i 1-(pyridin-2-yl)ethanol. Reaction conditions: 3.0 g [PEG600(mim)2][NTf2]2-based hybrid catalyst (0.12 mg/g of enzyme loading), a solution of racemic alcohol (0.10 M) and vinyl acetate (0.40 M) in n-octane as the mobile phase, 60 oC, 2 mL h−1.

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